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The ATTAIN-MAINTAIN Phase 3 trial specifically evaluated this scenario, testing whether patients who had achieved weight loss with injectable GLP-1 receptor agonists (semaglutide or tirzepatide) could switch to oral orforglipron while maintaining their weight loss
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Dispense product onto fingertips, then press into forehead, each cheek, nose, and chin
1i,j), without notable effects on PPAR-expressing cells that lack incretin receptors (Fig
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