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Excess copper contributes to oxidative stress, inflammation, and potential toxicity, the opposite of what GHK-Cu is supposed to do. Researchers have generally found that GHK-Cu helps regulate copper rather than overload it, but the line between beneficial and harmful copper exposure depends on dose, tissue type, and individual biology

In many of these cases, people reported dosing errors, sometimes taking 10 times the recommended dose, according to multiple poison control centers

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Long-acting GLP-1RAs carry a boxed warning about the potential for thyroid C-cell tumors, which is based on animal data

Neuroscience 165(4):13451352 Ko M-H, Chen W-P, Lin-Shiau S-Y, Hsieh S-T (1999) Age-dependent acrylamide neurotoxicity in mice: morphology, physiology, and function