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According to the company's own disclosure, this data was self-reported by approximately 7,084 surveyed customers who checked in between January 2024 and April 2024
As a result, the increased secondary BAs can activate TGR5, which increases L-cells and GLP-1 secretion by inhibiting the RhoA/ROCK pathway and inducing YAP activation [157, 203]
Importantly, these events were generally considered mild and self-limiting
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