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Semaglutide has a longer track record and an oral formulation

Retatrutide , a triple receptor agonist targeting GLP-1, GIP, and glucagon receptors simultaneously, is in clinical development

A recent study reported that Hmox1 activation induces heme accumulation and drives cardiomyopathy through ferroptosis induction, whereas inhibition of Hmox1 reduced cardiac damage in SCD 46

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Trial design: Makary and Prasad also argued the two-study approach alone doesnt safeguard against green-lighting subpar drugs if all other aspects of trial design are deficient a line that caught our eye given the Moderna flu vaccine whiplash of the last week-plus