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In reality, cost is a major consideration for these weight loss medications, says Alyssa Dominguez, MD, an endocrinologist with Keck Medicine of USC

Timeline of Weight Loss: What to Expect Initial Phase: The First Few Weeks Side effects such as alteration in appetite and food choices occur early in the treatment period

During follow-up visits, healthcare providers can also monitor for potential complications or adverse effects

This cost is because of the many years spent on research, clinical trials, and getting the right paperwork done

the improvement effects of the NPs and MNs treatment groups were not obvious, while the GLP-1RAs@NPs, GLP-1RAs@NPs-WYRGRL and MNs/GLP-1RAs@NPs-WYRGRL groups could effectively alleviate cartilage destruction and osteophyte formation, especially the MNs/GLP-1RAs@NPs-WYRGRL group (Fig