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This copper-binding tripeptide is found in various human tissues and exhibits affinity for heparan sulfate proteoglycans in the extracellular matrix
EHMT2/G9a stood out as a potential target: it is an epigenetic regulator expressed in immune cells, including macrophages, and its previously determined half maximal effective concentration (EC 50 ) (PubChem AID: 504332) matches the effect range (10100 M) seen in our study 39
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Moreover, this molecule showed a promising hepatoprotective function in a murine model of acute liver injury (32)
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