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Further, it appears as though diets rich in saturated fatty acids could alter fast skeletal muscle troponin T (TNNT3 gene) expression through alternative splicing of pre-mRNA in rat skeletal muscle (Black et al., 2017), although it remains to be seen if HFD could also alter the expression of other proteins of the troponin complex (troponin C and troponin I)
Agliardi C, Guerini FR, Saresella M, et al
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Gao T, Zhang X, Zhao J, Zhou F, Wang Y, Zhao Z, et al
When these amino acids are used as carbon and nitrogen sources, they must be converted into glutamate, followed by a transamination reaction into -ketoglutarate and ammonia, which is then catabolised by glutamate dehydrogenase
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