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Phase 3 data will determine whether this difference persists in larger, more diverse populations with longer follow-up
For control, the calibration set consists of the [GSH] and [GSSG] measurements at PN11, PN13 and PN15, and the validation set contains the data at PN15, PN17 and PN28
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Seino Y, Yamazaki Y (2022) Roles of glucose-dependent insulinotropic polypeptide in diet-induced obesity
A recent study showed that Trx1 attenuates cigarette smoke extract-induced endoplasmic reticulum (ER) stress, ROS production, mitochondrial dysfunction, and mitophagy-mediated inflammasome activation while enhancing the activation of the Nrf2/HO-1 signaling pathway, contributing to the improved antioxidant and anti-inflammatory response in murine lungs [130]
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