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These findings provide direct genetic evidence that variation in the drug target genes contributes to inter-person variability in response and lay the foundation for precision medicine approaches in the treatment of obesity

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These include Contrave, Qsymia, and Orlistat, which work differently to suppress your appetite and reduce fat absorption

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Vomiting Vomiting was reported in about 30.9% of patients in the OASIS 4 trial, compared to 5.9% on placebo, and was more common during the dose-escalation period