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Among patients with mutations in exons 6 and 7, 41% and 56% of them displayed epilepsy, respectively

Nat Rev Mol Cell Biol 20(1):2137 Gholinezhad M, Sartipi B, Amjadi I (2024) Evaluation of the effects of melatonin-treated RAW macrophage cells in the A-375 melanoma cell line

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As noted above, 5-cholesten-3-one is not showing any activity with the mammalian enzymes, presumably due to steric hindrance by the bulky sidechain (Figure 8)