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With the advent of new technologies and a deeper understanding of neuronal metabolism, the field is poised for significant breakthroughs that could transform our approach to treating neurological disorders (Lee and Silva, 2009)
Ahmadi et al., 2020
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This includes people with pernicious anemia, a condition where the body lacks intrinsic factors, making it impossible to absorb B12 from food
Although the nanoparticle drug delivery system was not initially designed for LDL-receptor-mediated brain targeting, it was later found that apolipoprotein E would be absorbed on the polysorbate 80 coated nanoparticles upon incubation of the nanoparticles with human plasma resulting in LDL-receptor mediated BBB crossing
