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To assess the associations of semaglutide with recurrent CUD, the study population included 2034 patients who had active medical encounters for the diagnosis of obesity in 6/202112/2022, were for the first time (new users design) prescribed semaglutide or non-GLP-1RA anti-obesity medications during 6/202112/2022 (time zero or index event), had a diagnosis of CUD on or before the index event, and had a diagnosis of at least one of obesity-associated comorbidities on or before the index event

These include harmful processes like oxidative stress (Oxidative stress induced senescence) and cell death (Apoptosis)

Berberine may support 1.5-2 kg of weight loss over several months, compared to 12-15 kg with GLP-1 medications

Lancet 2019;394:121-30.PubMed 39

This weight loss medication has taken on a life of...