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Repeatedly injecting in the same location can cause lipohypertrophy, a buildup of scar-like fatty tissue under the skin
Using a Seahorse XF24 extracellular flux analyzer, researchers measured the oxygen consumption rate (OCR) and extracellular acidification rate (ECAR), and revealed that cisplatin-resistant ovarian cancer cells exhibited OCR levels approximately three to four times higher than those of parental ovarian cancer cells
And to understand what these shifts might mean for global pharmaceutical companies, look no further than the market for GLP-1 drugs, in particular
Nakahata Y et al
Safety, tolerability, relative bioavailability, pharmacokinetics, and pharmacodynamics of single and multiple doses of the novel oral bofanglutide in healthy Chinese participants, Diabetes Research and Clinical Practice, 239 , (113437), (2026)
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