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Answer: Good candidates are adults struggling with persistent hunger, a stalled response to GLP-1 medications, insulin resistance, or a long history of weight cycling, who want to address the hormonal driver of appetite rather than rely on restriction alone

doi: 10.1038/cdd.2013.180 101 JuckerM.WalkerL

However, as with any injection, there is a risk of side effects such as pain at the injection site, infection, or allergic reactions

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This leads to numerous effects such as: increased membrane rigidity decreased activity of membrane-bound enzymes (e.g