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Another indicator of a battery being ready for disposal is "puffing"
Phase 2 trials used a structured titration protocol, typically starting at 0.5 mg once weekly and escalating to maintenance doses of up to 12 mg once weekly
Goffin E, Pirson Y, Geubel A, et al
Genetic variation in GLP-1 receptor expression and metabolic pathways means some patients require higher doses than others to achieve comparable results
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