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First injection: severe redness, significant itching, 72+ hours Second injection: same or worse Third injection: same or worse Long-term outcome: requires intervention (technique optimization, antihistamines, or provider evaluation) The three-injection rule helps set expectations

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Alcohol swabs

Pediatr Nephrol 28:507510

Accordingly, PASC could be described as a SARS-CoV-2-induced chronic and self-perpetuating comprised state of m- Dys, where OxS potentially drives inflammation and shifts energy metabolism towards glycolysis while down-regulating OXPHOS 27,142,143