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Hu R, Wang MQ, Liu LY, et al
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When cost is excluded as a factor, the leading reason for discontinuation is gastrointestinal side effects, most notably nausea and vomiting, as reported by patients (Sikirica et al., 2017)
Research has characterised MT-II-induced anorexia in rodent feeding paradigms , examining food intake suppression kinetics, meal pattern changes, body weight effects with repeated administration, and the hypothalamic neurochemical changes including NPY/AgRP suppression and melanocortin pathway activation markers accompanying MT-II-induced anorexia
10.1111/dom.12932 182
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