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Semaglutide was effective in lowering the concentration of low density lipoprotein (0.16 mmol/L (0.30 to 0.02)) and total cholesterol (0.48 mmol/L (0.84 to 0.11))

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GLP-1 receptors are widely distributed throughout the central nervous system, including brain regions involved in reward processing, motivation, and addictive behaviorsparticularly the mesolimbic dopamine system, which includes the ventral tegmental area and nucleus accumbens

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