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Fernandez-Millan E, Martin MA, Goya L, Lizarraga-Mollinedo E, Escriva F, Ramos S, et al
Keeping a slight bend in elbows, raise arms out to the sides up to shoulder height
Liver fat, visceral fat, lipids, ketones, and insulin are real and measured, but no retatrutide trial has tested insulin sensitivity or longevity as an endpoint
Interestingly, these incretin-sensitising effects of metformin appear to be mediated by a peroxisome proliferator-activated receptor -dependent pathway, as opposed to the more commonly ascribed pathway of metformin action involving AMP-activated protein kinase
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