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Low doses of ketamine induce dissociative effects that non-medical users refer to as k-land, however, very high doses those leading to more pronounced immobilizing, dissociative, and hallucinatory effects can take one down a k-hole. Contrary to a therapeutic or medical setting, illicit ketamine use can set one up for a bad trip

Syntrophy via interspecies H 2 transfer between Christensenella and Methanobrevibacter underlies their global cooccurrence in the human gut

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Understanding these patterns helps set realistic expectations for patients beginning semaglutide therapy