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The rising incidence of obesity and a marked decline in physical activity have both exerted an influence on this increasing T2D trend [1]

Its more common in people with certain conditions like diabetes, high blood pressure, and sleep apnea, per Brigham and Womens Hospital

Add to this complexity the high cost of making and formulating such peptides, and a small molecule drug starts to look much more attractive

Even moderate alcohol intake can substantially reduce the caloric deficit necessary for weight loss, potentially explaining poor treatment response in otherwise adherent patients