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6, September: 3083-3092, 2018 Patients and Methods: This study included 30 female patients with melasma who were selected among those attending the Outpatient Clinic of Dermatology and Venereology De- partment, Tanta University Hospitals during the period between December, 2015 and February, 2017

Laboratory studies demonstrate that FOXO4-DRI can eliminate chemotherapy-induced senescent cells that may contribute to administration resistance, while the timing of senolytic administration relative to chemotherapy requires careful optimization in experimental designs

Some patients respond better to one GLP-1 drug than another due to genetic variation in GLP1R gene expression or differences in how their bodies metabolize each compound

Many practitioners also combine mesotherapy with other regenerative approaches