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A rapidly acting glutamatergic ARCPVH satiety circuit postsynaptically regulated by -MSH [published correction appears in nat neurosci
The SELECT trial, published in The Lancet (October 22, 2025), provides a landmark analysis confirming that the cardioprotective benefits of semaglutide extend beyond weight loss alone. The SELECT Trial: Study Overview The SELECT trial (NCT03574597) enrolled 17,604 participants aged 45 years and above across 41 countries and 804 sites
A recently published survey conducted among Israeli endocrinologists, internal medicine physicians and family physicians who practice obesity medicine reported that fewer than 50% of physicians discussed treatment duration with their patients, and 52% of patients discontinued therapy in the first 3 months
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