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In ischemic and degenerative diseases, propagation represents a mechanism of collateral tissue loss and therefore should ideally be contained
Possible side effects include injection-site irritation, mild flushing, and occasional water retention during early cycles
doi:10.1001/jamaoto.2016.1700
PCD occurs in 1-5 per 10, 000 population and most commonly manifests between ages 1-7 [28, 29]
However, they cannot easily be prevented
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