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By definition, a technology transfer ensures that a process developed at one site (lab or contract facility) can be replicated exactly at another, while maintaining product quality and yield ( [51] )
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The application of melatonin resulted in a decrease in the relative membrane-leakage rate and the inhibition of superoxide radicals (O 2 ), malondialdehyde (MDA) and hydrogen peroxide (H 2 O 2 ) production
Studies have used continuous daily dosing for up to 2 years without loss of efficacy
Multiple mechanisms have been proposed to explain these observations, though the precise pathways remain an active area of research
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