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The article states that clinical literature does not establish that GLP-1 agonists treat Hashimoto's or reduce thyroid antibody levels, and that no randomized trials have evaluated semaglutide or tirzepatide as a primary treatment for it

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Likewise, multiple large clinical studies with various GLP-1 RAs have shown a more favorable trend in lipid profiles with GLP-1 RAs, although these were not evaluated as the primary outcomes (Table 2)

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