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Oxidative metabolism signatures predict response to 5FU-based chemotherapy treatment Given this robust adaptation to facilitate cellular survival in cancer cells treated with 5FU, we next postulated that elevated mitochondrial metabolism may be a predictor of response to 5FU-based chemotherapy

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Results The levels of GLP-1R decreased significantly in the knees of OA rats, accompanied by the downregulation of PKA /CREB signals and upregulation of inflammation-related proteins

Moreover, it makes the case that obesity (and its metabolic consequences) is the underpinning of HFpEF