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Following the final injection of rats with PTZ, animals were transferred individually to a clear plastic box (40 cm 40 cm 80 cm) for recording and evaluation of epileptic behavior

RT-qPCR further revealed considerable increases in the transcription of the ferroptosis sensitivity marker ACSL4 27 and ferroptosis regulatory factor HMOX1 ( HO-1 ) 28 , while most other ferroptosis-related genes showed minimal alterations at mRNA level (Supplementary Fig

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