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The study concludes that DSIPs activating action on oxidative phosphorylation and its preventive effects under hypoxia provide a strong basis for understanding its previously reported stress-protective and antioxidant actions in vivo

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Chronic psychological stress raises cortisol and inflammatory cytokines, both of which consume glutathione

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ROS-induced apoptosis is also correlated with increased expression or activity of the tumor suppressor protein p53 (TP53) [120]