It is a modified derivative of angiotensin IV, a component of the renin-angiotensin system involved in blood pressure regulation and, intriguingly, cognitive function
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In a double-blind study with a placebo group, chronic insomniac patients administered with a DSIP analogue experienced a reduction in sleep latency by an average of 22 minutes, suggesting its potential as a therapeutic agent for severe chronic insomnia patients (Anderer & Saletu, 1991)
In peptide research, this is critical
DSIP appears to influence sleep architecture itself, specifically the delta-wave (deep) stages