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10.1007/3-211-30714-1_43 Acta Neurochir
A large retrospective analysis of 237,043 patients with hip or knee OA, including 23,000 individuals exposed to GLP-1 agonists for at least 1 year, found that arthroplasty risk at 1 year was reduced by approximately 40% for hip replacement and 25% for knee replacement
Slows down the rate of product drying A vitamin C derivative that is more stable but less potent than pure form of vitamin C
1 Newer evidence shows these benefits extend beyond people with diabetes
Table 1: Sitagliptin and Metformin Co-administered to Patients with Type 2 Diabetes Inadequately Controlled on Diet and Exercise: Adverse Reactions Reported (Regardless of Investigator Assessment of Causality) in 5% of Patients Receiving Combination Therapy (and Greater than in Patients Receiving Placebo)* Sitagliptin Add-on Therapy in Patients with Type 2 Diabetes Inadequately Controlled on Metformin Alone In a 24-week placebo-controlled trial of sitagliptin 100 mg administered once daily added to a twice daily metformin regimen, there were no adverse reactions reported regardless of investigator assessment of causality in 5% of patients and more commonly than in patients given placebo
