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Certain groups may be more vulnerable to the effects of muscle loss: Older adults Individuals with low baseline muscle mass People who are physically inactive Women in perimenopause or postmenopause In these populations, muscle loss can contribute to sarcopenia (age-related muscle decline) and increase the risk of falls, frailty and reduced independence

Managing Sleep Disruption in Early GLP-1 Treatment Some individuals experience initial insomnia or frequent nighttime waking during the first few weeks on compounded semaglutide or tirzepatide, particularly if dosing escalates quickly

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