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Peptide Therapy GHK-Cu: COPPER PEPTIDE THERAPY A naturally occurring peptide that declines with age
In HFpEF models, TMAO impairs diastolic function by inhibiting Piezo1 expression and disrupting mechanotransduction ( 2+ influx, blocking the TRPV4-NO pathway to reduce endothelial NO production and compromise vasodilation (Zhang et al., 2024)
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