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Internal hemorrhoids occur inside the rectum and are generally painless, while external hemorrhoids develop under the skin around the anus and can be quite painful
Oxidative stress occurs when you have too many free radicals molecules with an odd number of electrons floating around in your body and not enough antioxidants to neutralize them
When inflammation causes ITT levels to plummet below this threshold, a chain reaction of pathology is initiated: first, the blood-testis barrier (BTB) loses its dynamic remodeling capacity, and tight junction proteins disassemble, preventing germ cells from successfully migrating across the barrier toward the luminal side (158161)
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