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showed an increase in RAI-uptake upon treatment with rosiglitazone (Philips et al., 2004)
For ultra-orphan drugs at prices of $300,000 to $500,000 per patient year, seven years of exclusivity on a 3,000-patient market can generate more than $1 billion in cumulative revenue
This effect is also seen in people with diabetes related high blood pressure and in pregnant women with pregnancy induced hypertension
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