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Overall, this study provides important support for clinical decision-making and highlights potential directions for future research on migraine prevention

Adjustments to diabetes or other medications should only be made under medical supervision

Understanding these interactions is crucial to avoid complications such as hypoglycemia (low blood sugar), bleeding, or reduced therapeutic benefits

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This MC1R selectivity makes it a more targeted research tool for melanocyte biology studies, though it retains measurable activity at other melanocortin receptor subtypes in binding assays