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RetzlerRx products are selected as part of an evidence-based preventive longevity medicine approach

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15 Quercetin has been demonstrated to prevent neuronal injury via inhibition of oxidative stress mediated inflammation (via NLRP3 inflammasome activation) in microglia through promoting mitophagy (breakdown of mitochondria, particularly those which are dysfunctional), which provides a potential novel therapeutic strategy for neuroinflammation-related diseases

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In fact AR231453, a selective GPR119 agonist, improves glucose tolerance and insulin sensitivity in both WT and Gpr119 cell / , suggesting how insulin release is independent from pancreatic GPR119 but depends on gut incretin release (330)

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