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The trial enrolled 46 preschool children aged 35 years with a confirmed diagnosis of ASD, although the authors did not report the sex distribution, ASD subtypes, symptom severity, or comorbid conditions of the participants

These findings suggested that EV-derived VDAC1 protein has a critical role in activating the AMPK/mTOR pathway and conferring PTX resistance

The first published case report of semaglutide-associated injection site nodules documented a 75-year-old patient who developed these nodules within minutes of injection at the 1 mg dose, with each nodule taking 2 to 4 days to resolve completely