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The L-371,257 powder was dissolved in 10% dimethyl sulfoxide (DMSO) in phosphate buffered saline (PBS)
Its approved for weight loss in adults with obesity or overweight
miR-214, enriched in osteoclast-derived EVs, suppresses osteoblast activity by targeting activating transcription factor 4 (ATF4), linking miRNA signaling to cross-lineage regulation during bone remodeling (165)
Metabonomics study of urine and plasma in depression and excess fatigue rats by ultra fast liquid chromatography coupled with ion trap-time of flight mass spectrometry
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