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Diabetologia (2018) 61:28494
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The copper complex promotes antioxidant effects protecting dermal cells from oxidative stress, stimulates fibroblasts to increase extracellular matrix formation, and enhances hair follicle health by supporting hair root strength and growth
However, emerging data and mechanistic plausibility suggest that certain populations may be at higher risk of suboptimal intake or depletion, particularly with prolonged therapy, rapid weight loss, restricted dietary variety or pre-existing marginal nutrient status
GPR40 plays an anti-inflammatory, antioxidant and neuroprotective role, particularly when combined with PUFAs [64, 65]
