For keeping up the treatment, doses are usually given weekly to monthly
Some participants achieved weight loss of approximately 24% of body weight at 48 weeks approaching levels reported with some bariatric surgical procedures, though no direct head-to-head comparisons have been conducted and long-term durability beyond the trial period remains unknown
Here are the most common myths set against the medically accurate picture
The concerns about the adverse effects of non-noble varieties, produced by their undesirable composition of kavalactones and high concentrations of potentially harmful compounds (flavokavains, which are not present in any significant concentration in the noble varieties), have led to legislation prohibiting exports from countries such as Vanuatu
It is important for patients and practitioners to understand that 'investigational' or 'research' status does not equate to safety, efficacy, or regulatory approval for human use outside of controlled clinical trial settings