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What to Expect in Month 2 Peak nausea: Weeks 6-8 worst for most patients, especially mornings Food aversions: Foods you loved suddenly repulsive (especially meat, coffee) Early satiety: Feel full after 3-4 bites, physical discomfort if you push it Fatigue increases: Combination of medication adjustment and reduced calorie intake Bowel unpredictability: Constipation one day, diarrhea the next Mental fog: Some patients report difficulty concentrating Research from the New England Journal of Medicine on incretin therapies shows this peak-and-resolution pattern is universal across GLP-1 and GIP agonists

These anti-obesity medications can help prevent the development of Type 2 diabetes

You have a history of poor GI tolerability and want to start with the least-aggressive compound in the class

And the 12 mg group lost 24.2%, with participants still losing weight at the end of the trial period, meaning the maximum effect had not been reached

What to look for: Fentanyl test result listed on COA Should read Not Detected or Negative Red flag: No fentanyl screening appears on the COA