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The Lancet (2022) 13

Is this blend the same as EGRIFTA

Epub 2015 Nov 18

Patients with pernicious anemia, intrinsic factor deficiency, or renal impairment require provider oversight

Mechanistically it adds steric and electrostatic bulk at the same end of the molecule the binding proteins engage, deepening the reduction in affinity beyond what the single substitution achieves alone