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Based on the JAHA meta-analysis, there are approximately 25 additional DVT events per 10,000 person-years of GLP-1 agonist use
In clinical trials, tirzepatide 15mg produced average weight loss of 20.9% of body weight over 72 weeks (SURMOUNT-1), while semaglutide 2.4mg produced 14.9% over 68 weeks (STEP 1)
Future studies evaluating the combination of GLP-1RAs with statins or other lipid-lowering agents could provide further insights into the optimal treatment strategies for such patients
If you experience significant weight loss or gain, contact your healthcare provider
GLP-1 drugs increase these effects
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