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As to why the islet has mix-identity cells, the investigators underscore that the plasticity of the pancreatic islets (37), numerous regulatory factors, including GABA, and patterns of cellular neogenesis or dedifferentiation are all under investigation Rodent and human islet studies demonstrate the complex autocrine and paracrine signaling that underpin nutrient-responsive crosstalk amongst -, - and - cells

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10.2174/1381612824666180614082950 39 KlicekR.KolencD.SuranJ.DrmicD.BrcicL.AralicaG.et al (2013)

It encompasses the heart, autonomic nervous system, and adrenals

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