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Preliminary findings point to possible contributions to astrocyte functioning and the regulation of brain-derived neurotrophic factor (BDNF), a molecule central to neuronal stability and neurogenesis
Role of copper and ceruloplasmin in oxidative mutogenesis induced by the glutathione--glutamyl transpeptidase system and by other thiols
the lysine residue preceding the active site, which forms electrostatic interactions with the carboxyl group of the glycine in GSH, the active site cysteines and polar amino acids interacting with the carboxyl group of the glutamate in GSH are conserved in most ROXYs, suggesting that GSH binding might be required for activity
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Our findings revealed that all agents and relevant combinations (i.e., GEP44 and GEP12 with Y1-R antagonists or Ex-4 alone) resulted in decreased glucagon release
