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Early evidence suggests that GLP1 receptor agonists may influence reward pathways related to alcohol intake, but findings are preliminary and not yet practicechanging
Sweeney et al., 2018)
60 In contrast, the long-acting enzyme resistant form of GLP-2, namely (Gly2)GLP-2, did not provide benefit on bone strength in a mouse model of bone fragility, 61 despite promoting the expression of bone matrix genes and reducing osteoclast number in the in vitro setting
These medications are contraindicated in pregnancy, and effective contraception is required during treatment
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