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Therapeutic Benefits: Matrix protein synthesis Stimulates collagen I, III, VII and elastin production Antioxidant amplification Enhances superoxide dismutase and catalase activity Tissue remodeling Balances collagen degradation and synthesis Vascular enhancement Promotes microcirculation and nutrient delivery Follicular activation Stimulates hair growth and scalp health Barrier optimization Strengthens skin protective mechanisms NAD+ (Nicotinamide Adenine Dinucleotide) Cellular Bioenergetic Optimizer NAD+ represents a paradigm shift in cellular anti-aging medicine, targeting the fundamental energy-producing mechanisms that govern cellular health, DNA repair, and metabolic function

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Abbreviations PCOS: Polycystic ovary syndrome POI: Premature ovarian insufficiency GPX4: Glutathione peroxidase 4 GSH: Glutathione LPCAT3: Lysophosphatidylcholine acyltransferase 3 NCOA4: Nuclear receptor coactivator 4 ACSL4: Acyl-CoA synthetase long-chain family member 4 TfR1: Transferrin receptor 1 FPN: Ferroportin PUFAs: Polyunsaturated fatty acids ROS: Reactive oxygen species ALOX15: Arachidonate 15-lipoxygenase LOX: Lipoxygenase LIP: Labile iron pool IREB2: Iron-responsive element-binding protein 2 Tf: Transferrin FTH1: Ferritin heavy chain 1 FSH: Follicle-stimulating hormone LH: Luteinizing hormone NCOA4: Nuclear receptor coactivator 4 FSP1: Ferroptosis suppressor protein 1 ACSL4: Acyl-CoA synthetase long-chain family member 4 SCD1: Stearoyl-CoA desaturase 1 CD44: Cluster of differentiation 44 HO-1: Heme oxygenase-1 NRF2: Nuclear factor erythroid 2-related factor 2 References Stockwell BR, Friedmann Angeli JP, Bayir H, Bush AI, Conrad M, Dixon SJ, Fulda S, Gascn S, Hatzios SK, Kagan VE et al (2017) Ferroptosis: a regulated cell death nexus linking metabolism, redox biology, and disease

Sept 13: The FDA accepted for review Takedas Biologics License Application for a subcutaneous (SC) formulation of Entyvio for moderately to severely active Crohns disease following induction therapy with intravenous Entyvio

At Skin Renewal, our doctor-led approach ensures that each treatment plan is tailored to the unique needs of every patient