Importantly, microglia in this activated state also secrete pro-inflammatory cytokines such as TNF-, IL-1, and IL-6, which further amplify ROS production and reinforce the inflammatory state
By supporting a balance in pigment formation and protecting skin cells from free radical damage, it helps promote a brighter and more even-looking complexion over time
Although the limiting factor for glutathione synthesis is cysteine, the body's own synthesis of glycine is not always sufficient to replenish the glutathione reserves

Evidence base: Tyrosinase inhibition multiple in vitro and clinical studies confirm glutathiones capacity to inhibit tyrosinase and shift melanogenesis toward lighter phaeomelanin production Published RCTs randomised controlled trials have documented measurable skin lightening outcomes with IV glutathione administration compared to placebo in Asian skin type populations, including Fitzpatrick IIIV the most prevalent skin types among Mumbai patients Hepatic and antioxidant support extensive published evidence from hepatology and immunology supports IV glutathiones systemic detoxification and antioxidant mechanisms Safety profile when administered in appropriate concentrations by qualified medical professionals, IV glutathione has a well-established safety record across international clinical practice At Brilliance Cosmocare, IV Glutathione therapy is administered strictly within evidence-supported concentration ranges by trained medical staff not administered in the unregulated, high-dose formats that carry documented safety concerns

IV administration bypasses the digestive system entirely, delivering glutathione directly into the bloodstream for maximum absorption