Availability: 60 in stock Sequence: Ac-Nle-Asp(1)-His-D-Phe-Arg-Trp-Lys (1) Molecular Formula: C 50 H 68 N 14 O 10 Molecular Weight: 1025.182 g/mol PubChem CID: 9941379 CAS Number: 189691-06-3 Monoisotopic Mass: 1024.52428442 Polar Area: 379 Complexity: 1950 XLogP: 0.7 Heavy Atom Count: 74 Hydrogen Bond Donor Count: 13 Hydrogen Bond Acceptor Count: 12 Rotatable bond count: 17 Pubchem LCSS : Bremelanotide Laboratory Chemical Safety Summary PT-141 has been investigated for its role in centrally mediated sexual arousal pathways , primarily through activation of melanocortin receptors, with particular emphasis on MC4R signaling within hypothalamic and limbic circuits involved in motivational behavior [1,2]
It remains a research peptide only
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In summary, observational studies have not found an increased risk of PDAC during short term follow-up
J Cell Sci (2012) 125(Pt 16):385869.10.1242/jcs.104018 Summary Keywords pituitary tumors, dopamine, somatostatin, DRD2, SSTRs, filamin A Citation Peverelli E, Treppiedi D, Giardino E, Vitali E, Lania AG and Mantovani G (2015) Dopamine and Somatostatin Analogues Resistance of Pituitary Tumors: Focus on Cytoskeleton Involvement